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Scientist II

Contract: South San Francisco, California, US

Salary Range: 50.00 - 62.00 | Per Hour

Job Code: 365457

End Date: 2025-12-11

Days Left: 1 days, 14 hours left

Pay Range: $50 - $62/hour

Position Details

Industry: Pharmaceutical
Job Title: Scientist II
Location: South San Francisco, CA 94080 
Duration: 6 months (Possible extensions / conversion into full time)
 
Key Responsibilities:
•The Quantitative, Translational ADME Sciences (QTAS) department is seeking a highly motivated scientist to join the Biologics bioanalysis, characterization, and proteomics group. 
•The main function of this position is to develop and implement LC/MS (liquid chromatography/mass spectrometry)-based bioanalysis and in vitro characterization assays for novel biologics entities. 
•The successful candidate will be experienced in the development, optimization and implementation of novel and routine LC/MS-based bioanalytical methods to support in vivo PK, TK, and PK/PD studies as well as in vitro stability characterization of therapeutic proteins, peptides, and oligonucleotides. 
•The candidate will be responsible for sample preparation, method development, bioanalytical assay operations, data analysis, report generation, and data presentation.
 
Key tasks and responsibilities:
• Operate and maintain LC/MS instruments to generate high-quality experimental data.
• Perform affinity purification of therapeutic proteins (including but not limited to monoclonal and bispecific antibodies, antibody drug conjugates, antibody-siRNA conjugates, and fusion proteins) from biological matrices.
• Analyze data and maintain detailed, accurate and comprehensive study documentation in electronic laboratory notebooks.
• Facilitate assay optimization and implementation to ensure laboratory capacity and data quality.
• Communicate data interpretation internally and externally.
 
Qualifications:
•Degree in chemistry, pharmacology or other related fields. BS with 3+ years or MS with 2+ years in a pharmaceutical industry setting with a focus on mass spectrometry.
• Highly motivated, self-driven and results-oriented with excellent communication and presentation skills; capable of working both as a team player and individual contributor.
• Prior industry experience in drug discovery/development is preferred. In-depth understanding of PK, TK and PK/PD studies and corresponding bioanalytical assays as well as in vitro characterization assays is highly desired.
• Hands-on experience with QQQ (SCIEX), qTOF (Agilent, Bruker, SCIEX) and/or Orbitrap (Thermo) mass spectrometers is highly desired.
• Hands-on experience with automated liquid handling systems is highly desired.
• Hands-on experience with oligonucleotide analysis is highly desired.

The Company offers the following benefits for this position, subject to applicable eligibility requirements: medical insurance, dental insurance, vision insurance, 401(k) retirement plan, life insurance, long-term disability insurance, short-term disability insurance, paid parking/public transportation, paid time off, paid sick and safe time, hours of paid vacation time, weeks of paid parental leave, and paid holidays annually – as applicable.

Job Requirement
  • LC-MS
  • In Vivo
  • QQQ
Reach Out to a Recruiter
  • Recruiter
  • Email
  • Phone
  • Himanshu Singh
  • himanshu.ksingh@collabera.com
Apply Now
Apply Now
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