Scientist I

Contract: Irvine, California, US

Salary: $37.00 Per Hour

Job Code: 355822

End Date: 2024-12-12

Days Left: 17 days, 12 hours left

Pay: $33 - $37

Position Details:
 
Industry: Pharmaceutical
 
Duration: 12 months, with a possible extension
 
Job Roles & Responsibilities: 
  • Design and optimize protocols for the efficient and reproducible differentiation of iPSCs into specific cell types.
  • Characterize and validate the differentiated cells using molecular and functional assays to ensure their fidelity and functionality.
  • Develop and optimize advanced cell models, including co-culture systems, organoids, or tissue-on-a-chip platforms, using iPSC-derived cells to mimic physiological or disease conditions.
  • Optimize cell culture protocols, media formulations, and growth conditions to ensure the viability, functionality, and reproducibility of the developed cell models.
  • Work in a team environment and coordinate the design, development, and optimization of in vitro assays to support discovery research projects and target validation studies related to hair and skin diseases.
  • Collaborate with cross-functional teams, including biologists, engineers, and data scientists, to integrate the developed cell models into larger research projects, including supporting in vivo model development and in vivo studies.
  • Plan experimental approaches with supervisory guidance. Discuss, recommend, and modify experimental techniques as needed.
  • Document and interpret results in order to reach conclusions, discuss with the supervisor, and decide on subsequent experiments.
  • Prepare technical reports, presentations, and appropriate documentation of work performed. Assist supervisor in maintaining project documentation.
  • Attend and participate in lab, team, and departmental meetings. Presentation of data as required.
Qualifications :
  • Proven experience in, and proficiency in iPSC maintenance, reprogramming, and differentiation techniques using various differentiation protocols are required.
  • Proficiency in advanced cell culture techniques, including iPSC culture and differentiation, primary cell isolation, immortalized cell lines, three-dimensional (3D) cell culture systems, co-culture systems, and organoid culture systems.
  • Experience in characterizing and validating differentiated cells using functional assays and molecular markers.
  • Proven experience in molecular biology techniques for analysis of in vitro cell-based assays and ex vivo tissues and/or fluid (RNA isolation, qPCR, western blot, ELISA, Luminex, F/ISH, IHC, flow cytometry, etc).
  • Proficient in data analysis software suites (e.g., GraphPad PRISM, Excel, R, etc.).
  • Excellent problem-solving skills and the ability to troubleshoot technical issues independently.
  • Strong organizational skills and attention to detail to maintain accurate records and documentation.
  • Bachelor’s Degree or equivalent education, or Master’s Degree or equivalent education with years of experience.
Job Requirement
  • Cell Culture
  • iPSC
  • flow cytometry
  • Stem Cell
Reach Out to a Recruiter
  • Recruiter
  • Email
  • Phone
  • Himanshu Singh
  • himanshu.ksingh@collabera.com
Apply Now
Apply Now
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