To discuss more about this job opportunity, please reach out to Chitrank Rastogi (LinkedIn URL - https://www.linkedin.com/in/chitrank-rastogi-55119a102/), email your updated resume at Email - chitrank.rastogi@collabera.com or give me a call at (425) 523-1648. Thank you!

Pay Range - $35 to $40/hr. (negotiable)

Job Description:
Job Roles & Responsibilities:

• Company’s growing Genetic Medicine group at Company South San Fransisco is seeking a highly motivated Associate Scientist to apply cutting-edge technologies to deliver innovative new therapies.
• As an integral member of the Genetic Medicine Group, this individual will assist in activities related to lipid nanoparticle (LNP)-mRNA production, process development/optimization, and characterization.
• The successful candidate will have familiarity with or prior exposure to laboratory instrumentation/methods related to LNP formulation development, such as microfluidic mixers, dynamic light scattering, membrane-based filtration/dialysis, and fluorescent plate-based assays.
• The successful candidate is expected to either show potential in or have hands-on experience to produce and evaluate LNPs with the aim of supporting pipeline projects as well as supporting general laboratory activities.
• As one of the key team members this individual will work with the manager and scientists across different functional groups to help discover and develop next generation non-viral genetic medicine.
• The candidate will need to have excellent verbal and written skills and the ability to clearly present scientific concepts and results.

Key Responsibilities:

• Assist in production and characterization of mRNA-LNP formulations to support internal programs.
• Assist in lipid and reagent preparation for manufacturing process as well as aliquoting and accurate labeling for storage and subsequent stability analysis.
• Familiarity with analytical techniques including but not limited to DLS, HPLC, ELISA, SEC, bioconjugation and nucleic acid characterization.
• Work closely with manager and cross-functional team members on multiple projects simultaneously to collect and analyze data on a per project basis.
• Under manager’s supervision, interpret, summarize experimental data, and present experimental results at meetings as needed.
• Assist in ordering supplies and reagents from internal inventory and external vendors necessary to support the projects.
• Generate reliable and reproducible data in a timely manner. Read and adapt scientific literature to accomplish assignments.
• Maintain documentation, databases and laboratory electronic notebooks in compliance with the Company Laboratory Notebook Policy.
• Remain compliant with all departmental and corporate training.

Key Qualifications:

• BS or MS in Chemistry, Chemical Engineering, Biological Engineering, Pharmaceutical Science or a related field with a minimum of 0-2 years of relevant industry experience. Experience with nanoparticle design and characterization methods is preferred.
• Self-motivated, hard-working, detail-oriented, resourceful, and able to work in a fast-paced team environment.
• Good computer skills including Word, Excel, PowerPoint, and relevant scientific software such as Prism.
• Hands-on experience with nucleic acid characterization and nanoparticle formulation is a plus.
• Hands on experience with chemical conjugation to lipid and analytics is a plus.
• Having a basic understanding of immunology and cancer biology is a plus.

What are the top 3-5 skills, experience or education required for this position?    

• BS or MS in Chemistry, Biomedical Engineering, Pharmaceutical Science or related field- 0-3 years’ experience
• mRNA-loaded Lipid Nanoparticle Formulation & Characterization experience
• Techniques such as DLS, HPLC, SEC, RiboGreen
• Worked with PNI Microfluidic Mixer or Syringe Pump Mixer
• Performed purification using dialysis cartridges or Amicon centrifuge tubes.